May 15 @ 11:00 AM – 12:00 PM
Dr. Xing Dai
Professor, SOM – Biological Chemistry
University of California, Irvine
“Beauty is Skin Deep: Epithelial Stem Cell Plasticity, Immune Crosstalk, and Metabolism”
Abstract: Skin is a dynamic organ that relies on the proper regulation of adhesive properties and metabolic activities of epithelial stem and progenitor cells for optimal development, homeostasis, and regeneration. I will summarize our work on transcription factors that modulate epithelial-mesenchymal plasticity and how they coordinate epithelial fate with stem cell function. Additionally, I will discuss our findings on how skin epithelial stem and progenitor cells interact with immune cells to regulate inflammation. Finally, I will present our recent research on the role of amino acid metabolism in controlling the proliferation and differentiation of skin epithelial stem and progenitor cells.
Host: Yi Wang
Seminar will be held in person only.
For questions about this event, please contact Mayra Rubio at mrubio3@uci.edu.